Fibroblast growth factor 23 levels associate with AKI and death in critical illness
DE Leaf, KA Jacob, A Srivastava… - Journal of the …, 2017 - journals.lww.com
Elevated plasma levels of the osteocyte-derived hormone fibroblast growth factor 23
(FGF23) have emerged as a powerful biomarker of cardiovascular disease and death in
patients with CKD. Whether elevated urinary or plasma FGF23 levels are prospectively
associated with AKI and death in critically ill patients is unknown. We therefore conducted a
prospective cohort study of 350 critically ill patients admitted to intensive care units at an
academic medical center to investigate whether higher urinary FGF23 levels associate with …
(FGF23) have emerged as a powerful biomarker of cardiovascular disease and death in
patients with CKD. Whether elevated urinary or plasma FGF23 levels are prospectively
associated with AKI and death in critically ill patients is unknown. We therefore conducted a
prospective cohort study of 350 critically ill patients admitted to intensive care units at an
academic medical center to investigate whether higher urinary FGF23 levels associate with …
