Role of the hypothalamic arcuate nucleus in cardiovascular regulation

HN Sapru - Autonomic Neuroscience, 2013 - Elsevier
Recently the hypothalamic arcuate nucleus (Arc) has been implicated in cardiovascular
regulation. Both pressor and depressor responses can be elicited by the chemical
stimulation of the Arc. The direction of cardiovascular responses (increase or decrease)
elicited from the Arc depends on the baseline blood pressure. The pressor responses are
mediated via increase in sympathetic nerve activity and involve activation of the spinal
ionotropic glutamate receptors. Arc-stimulation elicits tachycardic responses which are …