Expression of extra domain A containing fibronectin in chronic cardiac allograft rejection
M Franz, A Berndt, K Grün, P Richter, H Kosmehl… - The Journal of heart and …, 2011 - Elsevier
BACKGROUND:: Cardiac allograft vasculopathy (CAV) and fibrosis are important in chronic
cardiac allograft rejection. The aim of our study was to analyze the up-regulation of extra
domain A (ED-A) containing fibronectin (ED-A+ Fn) in cardiac allografts after heterotopic rat
heart transplantation using a human recombinant antibody applicable for targeted drug
delivery. METHODS:: Cardiac allografts were subjected to immunofluorescence double
labelling procedures combining a human recombinant small immunoprotein (SIP) format …
cardiac allograft rejection. The aim of our study was to analyze the up-regulation of extra
domain A (ED-A) containing fibronectin (ED-A+ Fn) in cardiac allografts after heterotopic rat
heart transplantation using a human recombinant antibody applicable for targeted drug
delivery. METHODS:: Cardiac allografts were subjected to immunofluorescence double
labelling procedures combining a human recombinant small immunoprotein (SIP) format …