Expression of HSPA12B in acute cardiac allograft rejection in rats

J Shi, D Yang, X Cong, Y Li, X Yang, Y Liu - Pathology-Research and …, 2015 - Elsevier
HSP70 may play a more important role in regulating antigen-specific immune response than
other HSPs; however, HSPA12B production in transplanted heart remains obscure, which
was identified as the newest member of the HSP70 family. In the current study, we
performed a heart transplantation model in adult rats and investigated the dynamic changes
of HSPA12B expression in the cardiac grafts. The cardiac grafts of allogeneic (Wistar–Lewis
rat) and syngeneic (Lewis–Lewis rat) rat models were subjected to histopathological and …