Muscular weakness in the mdx mouse
F Muntoni, A Mateddu, F Marchei, A Clerk… - Journal of the neurological …, 1993 - Elsevier
Abstract mdx mice are believed to be virtually free from neuromuscular symptoms, despite
the presence of a degenerative/regenerative process that involves all skeletal muscles. We
analyzed both the spontaneous motility and treadmill motor activity of mdx mice aged 15
days to 6 months. Our results indicate that there is an early period, between the end of the
second and up to the fifth week of life, when mdx mice experience extreme weakness. After
this critical period, both spontaneous motility and endurance of mdx mice, although lower …
the presence of a degenerative/regenerative process that involves all skeletal muscles. We
analyzed both the spontaneous motility and treadmill motor activity of mdx mice aged 15
days to 6 months. Our results indicate that there is an early period, between the end of the
second and up to the fifth week of life, when mdx mice experience extreme weakness. After
this critical period, both spontaneous motility and endurance of mdx mice, although lower …