Designing clinical trials in acute kidney injury
BA Molitoris, MD Okusa, PM Palevsky… - Clinical Journal of the …, 2012 - journals.lww.com
Diagnostic and therapeutic approaches to AKI secondary to ischemia, sepsis, and
nephrotoxins are receiving increasing attention as the effects of AKI on hospitalization,
morbidity, and mortality and on the acceleration of CKD progression to ESRD are becoming
better illuminated. Numerous studies have delineated the high mortality risk in patients with
AKI, especially in patients with sepsis or trauma and in patients undergoing cardiovascular
surgery (1). The National Institutes of Health (NIH) has promoted interest in developing …
nephrotoxins are receiving increasing attention as the effects of AKI on hospitalization,
morbidity, and mortality and on the acceleration of CKD progression to ESRD are becoming
better illuminated. Numerous studies have delineated the high mortality risk in patients with
AKI, especially in patients with sepsis or trauma and in patients undergoing cardiovascular
surgery (1). The National Institutes of Health (NIH) has promoted interest in developing …