Lymphocyte traffic changes induced by monolateral vagal denervation in mouse thymus and peripheral lymphoid organs

A Antonica, E Ayroldi, F Magni, N Paolocci - Journal of neuroimmunology, 1996 - Elsevier
In this report we show that after monolateral vagal denervation (vagotomy), performed at the
cervical level, a transient effect, lasting about 24 h, was produced on lymphocyte release
from mouse thymus to peripheral lymphoid organs (spleen and lymph nodes). Labelling
thymocytes in situ with fluorescein isothiocyanate (FITC) we note that the export of immature
cells, CD4+ CD8+, double positive (DP), and double negative, CD4− CD8−(DN), from the
thymus was consistently increased 24 and 48 h after vagotomy. Double staining with anti …