[HTML][HTML] Mechanisms of dense core vesicle recapture following “kiss and run”(“cavicapture”) exocytosis in insulin-secreting cells
T Tsuboi, HT McMahon, GA Rutter - Journal of Biological Chemistry, 2004 - ASBMB
The molecular mechanisms underlying" kiss and run" or" cavicapture" exocytosis of dense
core secretory vesicles are presently unclear. Although dynamin-1 has previously been
implicated in the recapture process in neurons, the recruitment of this fission protein to a
single exocytosing vesicle has not been examined in real time during peptide release from
pancreatic β-cells. Imaged simultaneously in clonal insulin-secreting cells by dual color total
internal reflection fluorescence microscopy, monomeric red fluorescent protein (mRFP) …
core secretory vesicles are presently unclear. Although dynamin-1 has previously been
implicated in the recapture process in neurons, the recruitment of this fission protein to a
single exocytosing vesicle has not been examined in real time during peptide release from
pancreatic β-cells. Imaged simultaneously in clonal insulin-secreting cells by dual color total
internal reflection fluorescence microscopy, monomeric red fluorescent protein (mRFP) …