Suppressing the antibody response with Siglec ligands

L Nitschke - New England Journal of Medicine, 2013 - Mass Medical Soc
New England Journal of Medicine, 2013Mass Medical Soc
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Production of antibodies to self-antigens is a risk factor for autoimmune disease. A potential strategy to suppress production of specific antibodies by B cells may involve stimulation of a class of “repressor” receptors, the sialic acid–binding immunoglobulin-like lectins.
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