[CITATION][C] Studies on salicylates and complement in diabetes

EDU Powell, RA Field - Diabetes, 1966 - Am Diabetes Assoc
EDU Powell, RA Field
Diabetes, 1966Am Diabetes Assoc
Increased levels of complement have been found in diabetic patients, being often more
marked in young patients with proliferative retinopathy. Neither duration of diabetes nor the
giving of insulin was associated with any particular alteration of complement levels.
Acetylsalicylic acid was effective in suppressing complement in vitro in all instances, but to a
greater extent in the younger, more severely affected patients. These findings are discussed
and related to mechanisms in production of retinopathy.
Increased levels of complement have been found in diabetic patients, being often more marked in young patients with proliferative retinopathy. Neither duration of diabetes nor the giving of insulin was associated with any particular alteration of complement levels. Acetylsalicylic acid was effective in suppressing complement in vitro in all instances, but to a greater extent in the younger, more severely affected patients.
These findings are discussed and related to mechanisms in production of retinopathy.
Am Diabetes Assoc