Interferon regulatory factors are a growing family of transcription factor that have been
implicated in cellular events such as cell-growth regulation, antiviral defense, and
development of the immune system. Interferon regulatory factor 7 (IRF-7) is expressed
predominantly in lymphoid tissues and has been studied extensively in the context of viral
infection and the induction of interferon and cytokine gene expression. In this paper, the
involvement of IRF-7 in monocyte differentiation was examined in U937, HL60, and human …