Monocytes recruited into tissues from peripheral blood differentiate into macrophages, which
are critical in the pathogenesis of many diseases. There is limited data concerning the
global changes in the expression of genes during monocyte to macrophage differentiation,
and how the patterns of change identify the mechanism contributing to macrophage
differentiation or function. Employing microarray technology, we examined the
transcriptional profile of in vitro adherence-induced differentiation of primary human …