Therapeutic interventions for symptomatic treatment in Huntington's disease
T Mestre, J Ferreira, MM Coelho… - Cochrane Database …, 2009 - cochranelibrary.com
T Mestre, J Ferreira, MM Coelho, M Rosa, C Sampaio
Cochrane Database of Systematic Reviews, 2009•cochranelibrary.comBackground Huntington's disease (HD) is an orphan autosomal dominant
neurodegenerative disorder caused by the amplification of a nucleic acids triplet repeat. It is
characterised by core symptoms of chorea, progressive dementia and psychiatric
manifestations such as depression, irritability, apathy and psychosis. In current clinical
practice, drugs exist that seem to improve symptoms for HD patients. However, their
effectiveness has not been fully measured. Objectives
neurodegenerative disorder caused by the amplification of a nucleic acids triplet repeat. It is
characterised by core symptoms of chorea, progressive dementia and psychiatric
manifestations such as depression, irritability, apathy and psychosis. In current clinical
practice, drugs exist that seem to improve symptoms for HD patients. However, their
effectiveness has not been fully measured. Objectives
Background
Huntington's disease (HD) is an orphan autosomal dominant neurodegenerative disorder caused by the amplification of a nucleic acids triplet repeat. It is characterised by core symptoms of chorea, progressive dementia and psychiatric manifestations such as depression, irritability, apathy and psychosis. In current clinical practice, drugs exist that seem to improve symptoms for HD patients. However, their effectiveness has not been fully measured.
Objectives
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