[HTML][HTML] Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20: EVIDENCE AGAINST INVOLVEMENT …
JP Deans, L Kalt, JA Ledbetter, GL Schieven… - Journal of Biological …, 1995 - ASBMB
CD20, a non-glycosylated cell-surface protein expressed exclusively on B lymphocytes, is
one of a family of 4-pass transmembrane molecules that also includes the β chain of the
high affinity receptor for IgE. The precise function of CD20 is unknown, although in vitro
effects of CD20-specific antibodies on resting B cells indicate that it is able to transduce an
extracellular signal affecting the G 0/G 1 cell cycle transition. Previous studies have
demonstrated that CD20-initiated intracellular signals involve tyrosine kinase activation and …
one of a family of 4-pass transmembrane molecules that also includes the β chain of the
high affinity receptor for IgE. The precise function of CD20 is unknown, although in vitro
effects of CD20-specific antibodies on resting B cells indicate that it is able to transduce an
extracellular signal affecting the G 0/G 1 cell cycle transition. Previous studies have
demonstrated that CD20-initiated intracellular signals involve tyrosine kinase activation and …
