[Frontiers in Bioscience 11, 479-491, January 1, 2006] 479 Matrix metalloproteinases: roles in
cancer and metastasis Barbara Fin Page 1 [Frontiers in Bioscience 11, 479-491, January 1,
2006] 479 Matrix metalloproteinases: roles in cancer and metastasis Barbara Fingleton Dept of
Cancer Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA TABLE OF
CONTENTS 1. Abstract 2. Introduction 3. Positive and negative contributions of MMPs to tumor
progression 3.1. MMPs and invasion 3.2. MMPs and tumor growth 3.3. MMPs and angiogenesis …