Low hemoglobin is associated with increased serum levels of vascular endothelial growth factor (VEGF) in cancer patients
J Dunst, S Pigorsch, G Hänsgen… - Strahlentherapie …, 1999 - search.proquest.com
J Dunst, S Pigorsch, G Hänsgen, I Hintner, C Lautenschläger, A Becker
Strahlentherapie und Onkologie, 1999•search.proquest.comBackground Vascular endothelial growth factor (VEGF) is an endothelial cell specific
mitogen with strong angiogenic activity. Expression of VEGF may therefore be an indicator
for the angiogenic potential and biological aggressiveness of a tumor. Recently,
measurement of the VEGF-protein in sera has become available. We report results of serum-
VEGF in an unselected group of patients with cancer with special emphasis on a possible
role of anemia.
mitogen with strong angiogenic activity. Expression of VEGF may therefore be an indicator
for the angiogenic potential and biological aggressiveness of a tumor. Recently,
measurement of the VEGF-protein in sera has become available. We report results of serum-
VEGF in an unselected group of patients with cancer with special emphasis on a possible
role of anemia.
Abstract
Background
Vascular endothelial growth factor (VEGF) is an endothelial cell specific mitogen with strong angiogenic activity. Expression of VEGF may therefore be an indicator for the angiogenic potential and biological aggressiveness of a tumor. Recently, measurement of the VEGF-protein in sera has become available. We report results of serum-VEGF in an unselected group of patients with cancer with special emphasis on a possible role of anemia.
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