Ventricular fibrillation: how do we stop the waves from breaking?
Circulation research, 2000•Am Heart Assoc
Combined experimental and theoretical developments have demonstrated that in addition to
preexisting electrophysiological heterogeneities, cardiac electrical restitution properties
contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing
therapies that favorably alter electrical restitution properties have promise as a new
paradigm for preventing fibrillation.
preexisting electrophysiological heterogeneities, cardiac electrical restitution properties
contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing
therapies that favorably alter electrical restitution properties have promise as a new
paradigm for preventing fibrillation.
Abstract
—Combined experimental and theoretical developments have demonstrated that in addition to preexisting electrophysiological heterogeneities, cardiac electrical restitution properties contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing therapies that favorably alter electrical restitution properties have promise as a new paradigm for preventing fibrillation.
Am Heart Assoc