Filament instability and rotational tissue anisotropy: a numerical study using detailed cardiac models

WJ Rappel - Chaos: An Interdisciplinary Journal of Nonlinear …, 2001 - pubs.aip.org
The role of cardiac tissue anisotropy in the breakup of vortex filaments is studied using two
detailed cardiac models. In the Beeler–Reuter model, modified to produce stable spiral
waves in two dimensions, we find that anisotropy can destabilize a vortex filament in a
parallelepipedal slab of tissue. The mechanisms of the instability are similar to the ones
reported in previous work on a simplified cardiac model by Fenton and Karma [Chaos 8, 20
(1998)]. In the Luo–Rudy model, also modified to produce stable spiral waves in two …