Vortex dynamics in three-dimensional continuous myocardium with fiber rotation: Filament instability and fibrillation

F Fenton, A Karma - Chaos: An Interdisciplinary Journal of Nonlinear …, 1998 - pubs.aip.org
Wave propagation in ventricular muscle is rendered highly anisotropic by the intramural
rotation of the fiber. This rotational anisotropy is especially important because it can produce
a twist of electrical vortices, which measures the rate of rotation (in degree/mm) of activation
wavefronts in successive planes perpendicular to a line of phase singularity, or filament.
This twist can then significantly alter the dynamics of the filament. This paper explores this
dynamics via numerical simulation. After a review of the literature, we present modeling tools …