[HTML][HTML] Vascular Endothelial Growth Factor, a Potent and Selective Angiogenic Agent (∗)
KA Thomas - Journal of Biological Chemistry, 1996 - ASBMB
The vascular system is essential for providing oxygen and nutrients, removing metabolic
waste products, and furnishing efficient access of leukocytes to tissues throughout larger
animals. Angiogenesis, the sprouting of new capillaries, is required for the development of
the vascular system and, consequently, the growth of vertebrates. Angiogenic proteins,
including several from the fibroblast growth factor family, were identified and purified in the
1980s. They were, however, found to be mitogenic not only for vascular endothelial cells but …
waste products, and furnishing efficient access of leukocytes to tissues throughout larger
animals. Angiogenesis, the sprouting of new capillaries, is required for the development of
the vascular system and, consequently, the growth of vertebrates. Angiogenic proteins,
including several from the fibroblast growth factor family, were identified and purified in the
1980s. They were, however, found to be mitogenic not only for vascular endothelial cells but …