Stranger in a strange land: the pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and arteries

JL Cox, DA Chiasson, AI Gotlieb - Progress in cardiovascular diseases, 1991 - Elsevier
The USE OF saphenous vein grafts (SVG) in coronary artery bypass graft (CABG) surgery is
the mainstay of the surgical treatment of ischemic heart disease. lm3 Less than 3% of
patients die perioperatively; thereafter, the annual mortality rate in the first 5 years is less
than 1.5%. 4-6 However, vein graft occlusion remains a major short-and long-term problem.'-
” In the first month after surgery, as many as 12% of grafts occlude with an additional 10% of
grafts occluding during the following 11 months.” By 5 years, about 65% of grafts remain …