Small peptides radiolabeled with 99mTc.
J Lister-James, BR Moyer, T Dean - The quarterly journal of nuclear …, 1996 - europepmc.org
J Lister-James, BR Moyer, T Dean
The quarterly journal of nuclear medicine: official publication of the …, 1996•europepmc.orgMethods Physical and chemical characteristics which affect pharmacokinetics are discussed
with particular reference to lipophilicity, charge and resistance to peptidases. General
biodistribution, pharmacokinetics, metabolism and excretion characteristics, as well as
tissue uptake kinetics are described. Methods of radiolabeling small peptides with 99mTc
are reviewed, including discussion of chelating groups for technetium. Specific examples
drawn either from the literature or from the 99mTc labeled peptides under development by …
with particular reference to lipophilicity, charge and resistance to peptidases. General
biodistribution, pharmacokinetics, metabolism and excretion characteristics, as well as
tissue uptake kinetics are described. Methods of radiolabeling small peptides with 99mTc
are reviewed, including discussion of chelating groups for technetium. Specific examples
drawn either from the literature or from the 99mTc labeled peptides under development by …
Methods
Physical and chemical characteristics which affect pharmacokinetics are discussed with particular reference to lipophilicity, charge and resistance to peptidases. General biodistribution, pharmacokinetics, metabolism and excretion characteristics, as well as tissue uptake kinetics are described. Methods of radiolabeling small peptides with 99mTc are reviewed, including discussion of chelating groups for technetium. Specific examples drawn either from the literature or from the 99mTc labeled peptides under development by Diatide are presented.
europepmc.org